Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 229-563-2 | CAS number: 6610-29-3
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The determination of the growth inhibition of the freshwater algae Pseudokirchneriella subcapitata exposed to the test item 4-methyl-3-thiosemicarbazide for a duration of 72 hours was assessed according to the OECD Guideline 201. ErC50-72h was determined as 30 mg/L
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 30 mg/L
- EC10 or NOEC for freshwater algae:
- 18 mg/L
Additional information
The determination of the growth inhibition of the freshwater algae Pseudokirchneriella subcapitata (previously known as Raphidocelis subcapitata and Selenastrum capricornutum) exposed to the test item 4-methyl-3-thiosemicarbazide for a duration of 72 hours was assessed according to the OECD Guideline 201.
Algae were exposed to 1 to 100 mg
4-methyl-3-thiosemicarbazide
/L dissolved in dilution water. The concentrations of test item causing a 50% reduction in biomass (EbC50) and in growth rate (ErC50) were estimated over a time period of 72 hours. The results were as follows:
Endpoint |
EC50-72h, mg/L (95%CI) |
EC10-72h, mg/L |
Cell growth – Biomass (b) |
26 (ND) |
15 (ND) |
Growth rate – Cell multiplication (r) |
30 (13 – 75) |
18 (2.9-32) |
CI: confidence interval; ND: not determined
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
