Registration Dossier
Registration Dossier
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EC number: 202-728-6 | CAS number: 99-08-1
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well documented study report which meets basic scientific principles
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 976
- Report date:
- 1976
Materials and methods
- Principles of method if other than guideline:
- Dermal exposure (24 hours) to 3-nitrotoluene
- GLP compliance:
- no
- Remarks:
- GLP was not mandatory at the time of the study
- Test type:
- standard acute method
Test material
- Reference substance name:
- 3-nitrotoluene
- EC Number:
- 202-728-6
- EC Name:
- 3-nitrotoluene
- Cas Number:
- 99-08-1
- Molecular formula:
- C7H7NO2
- IUPAC Name:
- 3-nitrotoluene
- Details on test material:
- - Name of test material (as cited in study report): m-nitrotoluole
- Physical state: Liquid (clear yellow)
- Analytical purity: no data
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
Administration / exposure
- Duration of exposure:
- 24 hours
- Doses:
- 1157 mg/kg bw
- No. of animals per sex per dose:
- 5
- Control animals:
- other: not applicable
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- > 1 157 mg/kg bw
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
