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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Description of key information

According to Column 2 of REACH Annex IX, long-term toxicity testing shall be proposed if the chemical safety assessment indicates the need to investigate further the effects on aquatic organisms. Based on the chemical safety assessment (section 13), there is no need to further investigate long-term toxicity.

Key value for chemical safety assessment

Additional information

Based on the approach taken in the chemical safety assessment, there is no need to investigate long-term toxicity to aquatic invertebrates.

Two supporting publications show that arthropods lack the ability to synthesize cholesterol and other sterols de novo and therefore have to acquire these essential compounds from their diet. Cholesterol is therefore the limiting factor for growth and reproduction. Addition of cholesterol to their diets increase the growth and clutch sizes significantly.