Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 276-594-2 | CAS number: 72361-35-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
Taking all available information into account the PFAE aromatic category members are unlikely to pose a risk for sediment organisms and testing is thus omitted
Key value for chemical safety assessment
Additional information
No experimental data evaluating the toxicity to sediment organisms is available for the category PFAE aromatic. Since the members of the category are considered as enhanced ultimately biodegradable, chronic exposure of sediment organisms is unlikely. In addition, available data indicate, that the members of the PFAE aromatic categroy are not bioaccumulative and not toxic to aquatic organisms up to the limit of water solubility. Based on the available information, toxicity to sediment organisms is not expected to be of concern.
Intrinsic properties and fate/ exposure
The members of the PFAE aromatics category are considered to be enhanced ultimately biodegradable, and therefore, they can be expected to undergo ultimate degradation in most environments, including biological Sewage Treatment Plants (STPs). Therefore, after passing through conventional STPs, only low concentrations of these substances are likely to be (if at all) released into the environment, where further biodegradation is expected.
Furthermore, the PFAE aromatic category members exhibit a log Koc value > 5 and are poorly water soluble (< 0.05 mg/L). The Guidance on information requirements and chemical safety assessment, Chapter R7.b (ECHA, 2012) states that once insoluble chemicals enter a standard STP, they will be extensively removed in the primary settling tank and fat trap and thus, only limited amounts will get in contact with activated sludge organisms. Nevertheless, once this contact takes place, these substances are expected to be removed from the water column to a significant degree by adsorption to sewage sludge (Guidance on information requirements and chemical safety assessment, Chapter R.7a, (ECHA, 2012)) and the rest will be extensively biodegraded. Thus, discharged concentrations of these substances into the aqueous/sediment compartment are likely to be negligible.
Considering this one can assume that the availability of the PFAE aromatic category members in the sediment environment is very low, which reduces the probability of chronic exposure of sediment organisms in general.
Aquatic ecotoxicity data
The available short-term and long-term data of the PFAE aromatic category show no toxicity up to the limit of water solubility (WS < 0.05 mg/L) in all trophic levels. The results obtained indicate that the PFAE aromatic category members are likely to show no toxicity to sediment organisms as well.
Metabolism/Bioaccumulation
Bioaccumulation is not expected for members of the PFAE aromatic category. Based on the molecular weight (546-757 g/mol), size and structural complexity of the substances the uptake from medium into sediment organisms is considered to be low (e.g. Dimitrov et al., 2002). Absorbed molecules of the category members will be metabolized and the metabolites will be excreted (for details see IUCLID section 5.3). Additionally, for substances with a log Kow value > 10, which have been calculated for the members of the PFAE aromatic category, it is unlikely that they reach the pass level of being bioaccumulative according to OECD criteria for the PBT assessment (BCF > 2000 L/kg; ECHA, 2012).
Furthermore the BCF/BAF values estimated with the BCFBAF v3.01 program, Arnot-Gobas model including biotransformation (BCF/BAF values of 0.89 L/kg and 0.89-10.92 L/kg, respectively), also indicate that this substance will not be bioaccumulative (all well below 2000 L/kg).
Conclusion
Due to their low water solubility, high adsorption potential and enhanced ultimate biodegradability, for all members of the PFAE aromatic category biodegradation in conventional STPs will take place and only low concentrations are expected to be released (if at all) into the environment. Absorption of the PFAE aromatic category members is not expected due to the molecular weight (546-757 g/mol), size and structural complexity of the molecules. Absorbed molecules will be metabolized and the metabolites will be excreted. Therefore, the potential for bioaccumulation is low. Furthermore, aquatic toxicity data show that no effects occur up to the limit of water solubility. Therefore, the PFAE aromatic category members are unlikely to pose a risk for sediment organisms in general and testing is thus omitted.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

EU Privacy Disclaimer
This website uses cookies to ensure you get the best experience on our websites.