Registration Dossier
Registration Dossier
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EC number: 294-620-0 | CAS number: 91744-56-8
Endpoint summary
Administrative data
Description of key information
Additional information
Glycerides, mixed C8-10 and succinyl (CAS No. 91744-56-8) is not expected to be volatile based on a vapour pressure value < 5 Pa at 20°C. Nevertheless, if released into the air, rapid indirect phototransformation (by reaction with OH-radicals) can be expected for this substance, based on estimated DT50 values ranging from 4.8 to 12.7 hours (AOPWIN v1.92). Hydrolysis is not expected to be a relevant degradation pathway for Glycerides, mixed C8-10 and succinyl due to the ready biodegradable nature of the substance. The estimated half-lives obtained with the HYDROWIN v2.00 program indicate that indeed, hydrolysis is not relevant for this substance (DT50 values 145 d-1.5 y at pH 7 and 14 d-55d at pH 8). In a biodegradation study performed according to OECD 301B, the substance reached 81.7% biodegradation in 28 days. Therefore, the substance is readily biodegradable and rapid biodegradation in both aquatic and terrestrial compartments is assumed. Due to the rapid environmental biodegradation and metabolization via enzymatic hydrolysis of Glycerides, mixed C8-10 and succinyl, a relevant uptake and bioaccumulation in aquatic organisms is not expected. Enzymatic breakdown will initially lead to the free fatty acid, glycerol and succinic acid. From literature it is well known, that these hydrolysis products will be metabolized and excreted in fish effectively)(Tocher, 2003; Lehninger, Nelson and Cox (1994); De Silva and Anderson, 1995). This is supported by estimated BCF values, ranging from 0.89 to 1 L/kg for this substance (BCFBAF v3.01, Arnot-Gobas, including biotransformation, upper trophic). Please refer to IUCLID Section 5.3.1 for a detailed overview on bioaccumulation of the Glycerides category members. Due to its expected high adsorption potential (log Kow > 10), if released into the environment the substance will tend to be mainly distributed in the soil and sediment compartments. Nevertheless, since Glycerides, mixed C8-10 and succinyl is readily biodegradable, persistence in these compartments is not expected.
A detailed reference list is provided in the technical dossier (see IUCLID, section 13) and within the CSR.
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