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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

EC50 > 100 mg/L can be reasonably extrapolated from activation sludge respiration inhibition tests performed according to OECD TG 209 for 1,3-dioxolane (EC50> 100 mg/L) and  2,5,7,10-TETRAOXAUNDECANE (EC50> 1000 mg/L), 2 members of the acetals familily (including also GF).

Methylal, another acetal, shows low toxicity to Pseudomonas putida with EC10 and EC50> 10 g/L (according to DIN 38412, part 8) and low toxicity to Pseudomonas fluorescens, Bacilius cereus, Enterobacter cloacae and S. cerevisae with inhibition concentrations of 40-50, 100-120 and 20-30 g/L, respectively.

This value is also supported by a supporting study in which no toxicity of GF was founf at concentrations of 7 mg/L.

Key value for chemical safety assessment

EC50 for microorganisms:
100 mg/L

Additional information