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Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

A 21d NOEC (reproduction) of 37 mg/L (measured) was determined for the read across substance methyl methacrylate.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
37 mg/L

Additional information

There is no data on the chronic toxicity of cyclohexyl methacrylate available. However, for the structurally related methyl methacrylate (CAS# 80-62-6) a 21 -d reproduction test, using Daphnia magna, exists (OECD guideline 211) (MPA, 1997). The test was conducted under flow through conditions. The 21 day EC50 for Daphnia magna was 49 mg/L and the NOEC for reproduction 37 mg/L, based on measured concentrations.

There is further a 21-day reproduction test with the hydrolysis product methacrylic acid (CAS# 79 -41 -4) available that was conducted according to OECD guideline 211 (MPA, 1995). Daphnia magna were exposed to the test substance at nominal concentrations of 13, 25, 50, 100 and 200 mg/L under flow through conditions. The LOEC was determined to be 110 mg/L. A NOEC of 53 mg/L was determined.