Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-943-5 | CAS number: 101-43-9
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A 21d NOEC (reproduction) of 37 mg/L (measured) was determined for the read across substance methyl methacrylate.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 37 mg/L
Additional information
There is no data on the chronic toxicity of cyclohexyl methacrylate available. However, for the structurally related methyl methacrylate (CAS# 80-62-6) a 21 -d reproduction test, using Daphnia magna, exists (OECD guideline 211) (MPA, 1997). The test was conducted under flow through conditions. The 21 day EC50 for Daphnia magna was 49 mg/L and the NOEC for reproduction 37 mg/L, based on measured concentrations.
There is further a 21-day reproduction test with the hydrolysis product methacrylic acid (CAS# 79 -41 -4) available that was conducted according to OECD guideline 211 (MPA, 1995). Daphnia magna were exposed to the test substance at nominal concentrations of 13, 25, 50, 100 and 200 mg/L under flow through conditions. The LOEC was determined to be 110 mg/L. A NOEC of 53 mg/L was determined.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
