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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

An OECD TG 203 study in compliance with GLP criteria with Fathead minnow (Pimephales promelas) is available for the test substance. Fish (10/concentration) were exposed to nominal concentrations of 10, 18, 29, 48 and 80 mg/L under static renewal conditions (media renewed after 48 hours) for 96 hours. The test concentrations were analytically verified and determined as 8.21, 15.1, 24.3, 42.5 and 73 mg/L (82 - 91% of nominal concentrations). Test conditions were maintained constant throughout the test. The dissolved oxygen concentration has been at least 60% of the air saturation value throughout the test. At 15.1 mg/L test level, 80% mortality was observed. At higher concentrations, mortality was 100%. Sublethal effects were also noted and consisted of one or more of the following: loss of equilibrium, immobilisation, lethargy. Based on these findings, the 96-hour LC50 was determined to be 11.8 mg/L (95% C.L. is 10.2 to 13.6 mg/L).

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Dose descriptor:
Effect concentration:
11.8 mg/L

Additional information