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Short-term toxicity to fish

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Description of key information

The short-term toxicity of Lyral to fish was determined in a GLP-compliant OECD 203 guideline study.  Fish (Pimephales promelas; 10/dose) were exposed to nominal concentrations of 10, 18, 29, 48 and 80 mg/L under static renewal conditions (media renewed after 48 hours) for 96 hours. The test concentrations were analytically verified and determined at 8.21, 15.1, 24.3, 42.5 and 73 mg/L (82 -91% of nominal concentrations).At the 15.1 mg/L test level, 80% mortality was observed. At higher Lyral concentrations mortality was 100%. Sublethal effects were also noted and consisted of one or more of the following: loss of equilibrium, immobilisation, lethargy. Test conditions were maintained constant throughout the test. The dissolved oxygen concentration has been at least 60% of the air saturation value throughout the test. Based on these findings the 96 -hour LC50 was determined at 11.8 mg/L (95% C.L. is 10.2 to 13.6 mg/L).

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
11.8 mg/L

Additional information