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Toxicity to microorganisms

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Description of key information

The toxicity of the test substance to microorganisms was determined as part of a toxicity control in a OECD TG 301D guideline study in compliance with GLP criteria. Secondary activated sludge (obtained from a wastewater treatment plant treating predominantly domestic wastewater) was exposed to 6.7 mg/L sodium acetate (positive control) with and without addition of 2 mg/L of the test substance. The oxygen depletion in both solutions was measured and compared. Inhibition of the degradation of sodium acetate by the addition of the test substance did not occur. Moreover, inhibition of the endogenous respiration of the inoculum by the test substance was also not detected. Based on the findings, the NOEC for microorganism toxicity was determined to be 2 mg/L.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
2 mg/L

Additional information