Registration Dossier
Registration Dossier
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EC number: 211-750-5 | CAS number: 693-36-7
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects have been observed in studies with sediment dwelling organisms:
In a GLP study according to OECD 225 no adverse effects to Lumbriculus variegatus were observed after 28 days up to the highest test concentration of 2000 mg/kg sediment dry weight.
Key value for chemical safety assessment
- EC10, LC10 or NOEC for freshwater sediment:
- 2 000 mg/kg sediment dw
Additional information
The long-term toxicity to freshwater sediment organisms was determined in a study according to OECD guideline No 225 and in compliance with GLP criteria. In this test, sediment worms (Lumbriculus variegatus) were exposed up to a nominal test substance concentration of 2000 mg/kg sediment dry weight for 28 days. Artificial sediment was used which contained 5 % peat, 20 % kaolin and 75 % quartz sand. The analysis of the test substance concentrations were technically not feasible. Therefore, all effect values are given as nominal. No mortality was observed in all test item concentrations. The total number of worms and thus the reproduction did not statistically significantly differ compared to the control in all test item concentrations.
Compared to the control, the total biomass per replicate was not statistically significantly different in all test item concentrations. Based on these findings the 28 -d NOEC is determined at 2000 mg/kg sediment dry weight.
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