Registration Dossier
Registration Dossier
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EC number: 279-632-6 | CAS number: 80939-62-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Based on the results of the available studies the LC50 for fish used for the risk assessment was determined to be 5.5 mg/L. However, the value is a worst case consideration due to several limitations of both studies.
Key value for chemical safety assessment
Additional information
Two studies on the short-term toxicity to fish are available, one with a coldwater fish (rainbow trout) and the other one with the warmwater fish zebra fish. Both studies was performed in accordance to OECD 203, but have several shortcomings (no analytics perfomed, high amount of solvent used). However, results of both studies can be used to determine the toxicity to fish, since, due to the high amount of emulsifier, the results represent a worst-case consideration.
In the first study (1984) the 96-h acute toxicity to rainbow trout (Oncorhynchus mykiss), exposed to test item at nominal concentrations of 0 (control, solvent control), 0.58, 1.00, 1.8, 3.2, 5.8 mg/L, was assessed under static conditions. The calculated and graphically determined 96-h LC50 based on mortality was 5.5 mg/L. The 96-h LC0, based on mortality, was 3.2 mg/L, respectively.
In the second study the acute toxicity of the test item to the warm water fish zebra-fish was determined under static conditions. Test organisms were exposed to nominal concnetrations of 0 (control, solvent control), 5.8, 10.0, 18.0, 32.0 and 58.0 mg/L. The graphically determined 96-h LC50 based on mortality was 10.8 mg/L, the 96-h LC0 was graphically determined to be 5.8 mg/L.
Based on the results of the available studies the LC50 for fish used for the risk assessment was determined to be 5.5 mg/L. However, the value is a worst case consideration due to several limitations of both studies.
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