Registration Dossier
Registration Dossier
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EC number: 500-018-3 | CAS number: 9005-64-5 1 - 6.5 moles ethoxylated
Endpoint summary
Administrative data
Description of key information
Additional information
Based on an experimental study, Sorbitan monolaurate, ethoxylated (CAS No. 9005-64-5) is readily biodegradable. According to OECD criteria (62.5% biodegradation after 28 d). Therefore, the substance will not be persistent in the environment. The degradation via abiotic hydrolysis is not considered to be a relevant degradation pathway in the environment since QSAR calculations using HYDROWIN v2.00 resulted in DT50 > 1 yr at pH 7. Evaporation into air and the transport through the atmospheric compartment is not expected based on the low vapour pressure.
Sorbitan monolaurate, ethoxylated is poorly soluble in water (< 0.2 mg/L at 20 °C, pH=6.3 - 7.9) and is expected to adsorb to solid soil/sediment particles. Although the log Koc values estimated by QSAR are relatively low (1.7 - 2.6, KOCWIN v2.00), the substance has surface active properties, which increases the adsorption potential, but is not taken into account by the model (Chu and So, 2001; Laha et al., 2009). Consequently, the main environmental target compartments for Sorbitan monolaurate, ethoxylated would be soil and sediment. However, the substance is expected to be eliminated extensively in sewage treatment plants, due to ready biodegradability and adsorption to sewage sludge. Release to surface waters and sediment, is therefore very unlikely. If the substance were to be released in the environment, it is expected to be rapidly degraded by microorganisms in both aquatic and terrestrial compartments.
Bioaccumulation is not expected for Sorbitan monolaurate, ethoxylated, based on low calculated BCF values of 1.2 - 7.1 L/kg ww (BCFBAF v3.01, Arnot-Gobas, including biotransformation, upper trophic). Moreover, the exposure via water is expected to be very low (low solubility and ready biodegradation) and the substance is expected to be digested by common metabolic pathways (Berg et al., 2002; Wick, 1953; Tocher, 2003).
References
Berg, J.M., Tymoczko, J.L. and Stryer, L. (2002) Biochemistry, 5th edition, W.H. Freeman and Company
Chu, W., So, W.S., 2001. Modeling the two stages of surfactant-aided soil-washing. Water Res. 35 (3), 182–188.
Laha, S., Tansel, B., Ussawarujikulchai, A., 2009. Surfactant-soil interactions during surfactant amended remediation of contaminated soils by hydrophobic organic compounds: a review. J. Environ. Manage. 90, 95–100.
Tocher, D.R. (2003):Metabolism and function of lipids and fatty acids in teleost fish,Reviews of Fisheries Science, 11 (2), 197
Wick A.N. and Joseph L. (1953): The metabolism of Sorbitan monostearate. Food Research, 18, 79
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