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Long-term toxicity to aquatic invertebrates

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Description of key information

NOELR (21d) 10 mg/L (OECD 211, Daphnia magna)

Key value for chemical safety assessment

Additional information

One study is available on the long-term toxicity of Sorbitan monolaurate, ethoxylated (CAS No. 9005-64-5) to aquatic invertebrates.

The key study conducted with Sorbitan monolaurate, ethoxylated (CAS No. 9005-64-5) was performed according to OECD Guideline 211 and GLP (Schlechtriem, 2012). The test organism Daphnia magna was exposed to the test substance under semi-static conditions, at nominal test concentrations of 1.0, 3.2, 10.0, 32.0 and 100 mg/L during 21 days. The test solutions were prepared as water accommodated fractions (WAF). At 32 mg/L, a significant effect on reproduction was observed. Also the body length of parent animals was affected by the treatment at this concentration, and 60% parental mortality occurred. At 100 mg/L, 100% mortality of the parent animals was observed. Therefore, reproduction could not be evaluated for this concentration. The NOELR for reproduction was thus determined to be 10 mg/L.