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Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1962
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Abstract only available, data not accessible by the registrant

Data source

Reference
Reference Type:
secondary source
Title:
Initial submission to US EPA regarding the toxicity of Bromoaceti acid in rats and rabbits
Author:
US EPA
Year:
1992
Bibliographic source:
US EPA National Technical Information Service (NTIS), microfiche No. OTS0555280, Doc ID 88-92-0008963

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
no data given
GLP compliance:
not specified
Test type:
other: 1 h inhalation screening
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Bromoacetic acid
EC Number:
201-175-8
EC Name:
Bromoacetic acid
Cas Number:
79-08-3
Molecular formula:
C2H3BrO2
IUPAC Name:
2-bromoacetic acid
Details on test material:
no data avaialble

Test animals

Species:
rat

Administration / exposure

Route of administration:
inhalation: aerosol
Type of inhalation exposure:
not specified
Vehicle:
not specified
Details on inhalation exposure:
no details given
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
ca. 1 h
Concentrations:
2 to 200 mg/L
No. of animals per sex per dose:
No data
Control animals:
not specified
Details on study design:
no data
Statistics:
no data

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
> 2 - < 200 mg/L air
Based on:
test mat.
Exp. duration:
1 h
Remarks on result:
other: no further data available

Applicant's summary and conclusion

Interpretation of results:
toxic
Remarks:
Migrated information class 3 Criteria used for interpretation of results: EU
Conclusions:
The data are of limited reliability as no details are given, but support the expected effects from a corrosive substance and the current classification as acute toxic class 3 by the inhalation route.
Executive summary:

The data are of limited reliability as no details are given, but support the expected effects from a corrosive substance and the current classification as acute toxic class 3 by the inhalation route.