Registration Dossier
Registration Dossier
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EC number: 201-175-8 | CAS number: 79-08-3
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1962
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Abstract only available, data not accessible by the registrant
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Initial submission to US EPA regarding the toxicity of Bromoaceti acid in rats and rabbits
- Author:
- US EPA
- Year:
- 1 992
- Bibliographic source:
- US EPA National Technical Information Service (NTIS), microfiche No. OTS0555280, Doc ID 88-92-0008963
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- no details given
- GLP compliance:
- not specified
- Test type:
- other: no data
- Limit test:
- no
Test material
- Reference substance name:
- Bromoacetic acid
- EC Number:
- 201-175-8
- EC Name:
- Bromoacetic acid
- Cas Number:
- 79-08-3
- Molecular formula:
- C2H3BrO2
- IUPAC Name:
- 2-bromoacetic acid
- Test material form:
- solid: crystalline
- Details on test material:
- solid moistened with water
Constituent 1
Test animals
- Species:
- rabbit
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- water
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 59.9 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: no details reported
- Clinical signs:
- severe skin irritation reported
Applicant's summary and conclusion
- Interpretation of results:
- toxic
- Remarks:
- Migrated information acute class 3 Criteria used for interpretation of results: EU
- Conclusions:
- The data are of limited reliability as no details are given, but support the expected effects from a corrosive substance and the current classification as acute toxic class 3 by the dermal route.
- Executive summary:
The data are of limited reliability as no details are given, but support the expected effects from a corrosive substance and the current classification as acute toxic class 3 by the dermal route.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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