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Vapour pressure

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vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
OECD Guideline 104 (Vapour Pressure Curve)
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: by loss of weight or by trapping vaporisate
20 °C
Vapour pressure:
< 0 hPa
25 °C
Vapour pressure:
< 0 hPa
50 °C
Vapour pressure:
< 0 hPa

Temperature (°C)

Vapour Pressure (p/hPa)

Cell A

Cell B


3.72 x 10-5

3.42 x 10-6


1.79 x 10-6

1.66 x 10-6


<1 x 10-6

<1 x 10-6

Vapour pressures were calculated using a molar mass of 316.40 g/mol. A vapour pressure equation and a vapour pressure curve was used to determine the vapour pressure at 20, 25 and 50°C. The vapour pressure curve is attached below (Attached background material: BPA EO OECD 104 Vapour Pressure Curve). At the temperature applied the vapour pressure descended perpetually at constant temperature and reached the identification limit of the most sensitive measurement technique.

The vapour pressure was determined as <1 x 10^-6 hPa (20°C), <1 x 10^-6 hPa (25°C) and <1 x 10^-6 hPa (50°C).
Executive summary:

The vapour pressure of the test substance was determined in accordance with the OECD Guideline for Testing of Chemicals 104. The vapour pressure was determined by the effusion method, weight loss, and was found to be <1 x 10-6 hPa (20°C), 1 x 10-6 hPa (25°C) and 1 x 10-6 hPa (50°C).

Description of key information

The vapour pressure was found to be 3.6 x 10^-4 Pa and 1.0 x 10^-4 Pa from two studies on the test material.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information

Two studies were conducted to assess the vapour pressure of the test substance. The studies were considered reliable as they were conducted on the registered substance according to OECD Testing Guideline 104. The key study was conducted using effusion method (vapour pressure balance), whilst the supporting study was conducted using effusion method (weight loss). The two studies produced comparable results at 25°C (3.6 x 10^-4 Pa from the key study, and 1.9 x 20^-4 Pa from the supporting study).