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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

Since dihydrogen hexafluorotitanate rapidly dissociates into fluoride, hydrogen and titanium ions upon dissolution in the environment, and only fluoride but not hydrogen and titanium ions will remain as such in solution, it can be assumed that toxicity (if any) will be driven by the fluoride anion. Therefore, full read-across of microbial toxicity data of potassium fluoride (CAS #7789-23-3) and other fluorides based upon a molecular weight conversion is justified (see below). The lowest available NOEC of 7.1 mg F/L for toxicity of fluoride to Uronema parduszi results in a NOEC for microbial toxicity of 10.2 mg/L dihydrogen hexafluorotitanate.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
10.2 mg/L

Additional information

Dihydrogen hexafluorotitanate

Since dihydrogen hexafluorotitanate rapidly dissociates into fluoride, hydrogen and titanium ions upon dissolution in the environment, and only fluoride but not hydrogen and titanium ions will remain as such in solution, it can be assumed that toxicity (if any) will be driven by the fluoride anion. Therefore, full read-across of microbial toxicity data of potassium fluoride (CAS #7789-23-3) and other fluorides based upon a molecular weight conversion is justified (see below). The lowest available NOEC of 7.1 mg F/L for tresults in a NOEC for microbial toxicity of 10.2 mg/L dihydrogen hexafluorotitanate.

Potassium fluoride

The guideline-compliant Bayer study reports a 3 -hour NOEC of 510 mg/L for activated sludge. The EU RAR summarises and reviews the other available data on the toxicity of fluoride to aquatic microorganisms; NOEC values of between 7.1 - 226 mg/L are reported.