Registration Dossier
Registration Dossier
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EC number: 221-921-6 | CAS number: 3282-30-2
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound: In contact with water, the substance will hydrolyse
rapidly.
Hydrolysis product pivalic acid: According to structural properties,
hydrolysis is not probable.
Key value for chemical safety assessment
Additional information
In a GLP guideline study following OECD TG 111 the test material has been determined to degrade spontaneously in aqueous media. No rate constant or half-life could be determined experimentally. Pivalic acid was determined as the major hydrolysis product (SafePharm, 2003).
According to Kollig et al. (1993), Boethling & Mackay (2000) and Harris (1990), pivalic acid is generally resistant to hydrolysis because it does not contain any labile functional groups.
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