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Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2003
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
Deviations:
yes
Remarks:
particle size dry powder module
Principles of method if other than guideline:
Coulter LS Particle size distribution
Optical system
LS 100 dry powder module
time: 30 s
vacuum step 7 rota 8
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Remarks:
Dry Powder Module
Type of distribution:
volumetric distribution
Percentile:
other: Average particle size
Mean:
77.63 µm
Remarks on result:
other: Standard deviation in µm
Remarks:
34.67 µm
Percentile:
other: D5
Mean:
147.2 µm
Remarks on result:
other: Standard deviation not determined
Percentile:
D10
Mean:
128.7 µm
Remarks on result:
other: Standard deviation not determined
Percentile:
D50
Mean:
70.3 µm
Remarks on result:
other: Standard deviation not determined
Percentile:
D90
Mean:
40.43 µm
Remarks on result:
other: Standard deviation not determined
Percentile:
D95
Mean:
34.11 µm
Remarks on result:
other: Standard deviation not determined

< 2 micrometer: 0 Vol%

> 200 micrometer: 0 Vol%

Description of key information

D50: 70.3 µm

Additional information