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EC number: 907-131-0 | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Additional information is available in the endpoint summaries and the read-across justification (see section 13).
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across: supporting information
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: test result from RA Source CAS 112-27-6 (Dawson, 1975)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 69 800 mg/L
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: test result from RA Source CAS 112-27-6 (Veith, 1983)
Reference
Description of key information
The 96-h LC50 value of main component triethylene glycol is > 10000 mg/L in freshwater fish. With high probability the test substance is acutely not harmful to fish.
Key value for chemical safety assessment
Additional information
Since no data on the short-term toxicity to fish of the reaction mass of 2,2'-(ethylenedioxy)diethanol 3,6,9-trioxaundecane-1,11-diol are available, the assessment is based on studies with the main component triethylene glycol (CAS 112-27-6).
The short-term toxicity to freshwater fish was determined in a published pre-GLP study (Dawson et al., 1975). In this study, groups of unknown quantity freshwater fish (Lepomis macrochirus) were exposed for 96 hours to nominal test concentrations of 7800 and 10000 mg/L under static conditions. Analytical verification of the test concentrations was not performed (not specified). Incidences of mortality were recorded daily. The 96-h LC50 was determined to be > 10000 mg/L.
As supporting data a publication is available that investigated the short-term toxicity to the fathead minnow (Pimephales promelas) (Veith et al., 1983). Test organisms were exposed to five test concentrations and a controlfor 96 hours under freshwater flowthrough conditions. The 96-h LC50 for the test substance was determined to be 69800 mg/L (nominal).
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