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Short-term toxicity to aquatic invertebrates

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Description of key information

The acute toxicity of sugar factory lime (SFL) to Daphnia magna has been investigated in a GLP study performed in accordance with OECD Guideline 202. The 48 h EC50 was >100 mg/L based on the water accommodated fraction.
The results from this study demonstrate that SFL is not acutely toxic to aquatic invertebrates.

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Additional information

The key study [Degussa (2007c)] was performed to OECD Guideline 202 and in accordance with GLP and was therefore assigned a reliability of 1. The study assessed the acute toxicity of Sugar Factory Lime (SFL) to Daphnia magna in a limit test. Since the test substance is a multi-component substance and is poorly soluble in water, the test was performed with the water-accommodated fraction (WAF) of 100 mg SFL/L medium. No toxic effects were seen at this test concentration. Hence, the 48 h EC50 was >100 mg/L.

The study for SFL is supported by an acute toxicity study to Daphnia magna performed with calcium carbonate (nano) [Priestly (2010b)]. The study assessed the acute toxicity of calcium carbonate (nano) to Daphnia magna in a limit test. No toxic effects were seen when a 100% v/v saturated solution of calcium carbonate was tested. Hence, the 48 h EC50 was >100% v/v saturated solution and the NOEC was 100% v/v saturated solution. The concentration of calcium carbonate (nano) that might cause acute toxicity is therefore greater than the maximum solubility of calcium carbonate in water.