Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only short abstract available.

Data source

Reference
Reference Type:
publication
Title:
Akrylove Slouleniny A Zdravotni Stav Exponovanicch Osob.
Author:
Kuzelova et al
Year:
1981
Bibliographic source:
Pracov. Lek. 33: 95-99.

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Butyl acrylate
EC Number:
205-480-7
EC Name:
Butyl acrylate
Cas Number:
141-32-2
Molecular formula:
C7H12O2
IUPAC Name:
butyl prop-2-enoate
Test material form:
other: liquid

Results and discussion

Clinical signs:
14/33 (42.3%) employees who were exposed for an average of 5 years to 50 mg/m3 butyl acrylate and 4 - 58 mg/m3 ethyl acrylate complained about nervous disorders. No changes were found in the EEG (electroencephalographic examination).

Applicant's summary and conclusion