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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

Determination of the toxicity of  m-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline in aquatic algae.

Key value for chemical safety assessment

EC50 for freshwater algae:
20 mg/L

Additional information

In 2007, two studies were performed on Algae to determine the toxicity of m-(2,3 -epoxypropoxy)-N,N-bis(2,3 -epoxypropyl)aniline and were considered as supporting study.

In the first experiment (SPL PROJECT NUMBER: 2345/0005), the effect of the test material on the growth of Desmodesmus subspicatus has been investigated over a 72-Hour period and gave an ErC 50 (0 - 72 h) of 15 mg/l, an EyC 50 (0 - 72 h) of 8.2 mg/l, and an EbC 50 (0 - 72 h) of 8.7 mg/1. The Lowest Observed Effect Concentration based on inhibition of growth rate, yield and biomass integral was 8 mg/l, and the No Observed Effect Concentration was 4 mg/l.

In the second eperiment, (SPL PROJECT NUMBER: 2345/0001), the effect of the test material on the growth of Desmodesmus subspicatus has been investigated over a 72-Hour period and gave an ErL 50 (0 - 72 h) of 57 mg/l loading rate WAF; 95% confidence limits 51-65 mg/l loading rate WAF, an EyL 50 (0 - 72 h) of 27 mg/l loading rate WAF; 95% confidence limits 24 - 30 mg/l loading rate WAF, and an EbL 50 (0 - 72 h) of 32 mg/1 loading rate WAF; 95% confidence limits 28 - 35 mg/1 loading rate WAF. The Lowest Observed Effect Loading Rates based on inhibition of growth rate, yield and biomass integral were 40, 20 and 20 mg/l loading rate WAF respectively, and the No Observed Effect Loading Rates were 20, 10 and 10 mg/l loading rate WAF respectively.

In the key study experiment, the effect of the test material on the growth of Pseudokirchneriella subcapitata has been investigated over a 72-hour period and gave an ErL 50 (0 - 72 h) of 57 mg/l loading rate WAF; 95% confidence limits 51-65 mg/l loading rate WAF, an EyL 50 (0 - 72 h) of 27 mg/l loading rate WAF; 95% confidence limits 24 - 30 mg/l loading rate WAF, and an EbL 50 (0 - 72 h) of 32 mg/1 loading rate WAF; 95% confidence limits 28 - 35 mg/1 loading rate WAF. The Lowest Observed Effect Loading Rates based on inhibition of growth rate, yield and biomass integral were 40, 20 and 20 mg/l loading rate WAF, respectively. The No Observed Effect Loading Rates were 20 (inhibition) 20 (yield) and 10 mg/l (biomass) loading rate WAF respectively.