Registration Dossier
Registration Dossier
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EC number: 217-288-0 | CAS number: 1800-91-5
Endpoint summary
Administrative data
Key value for chemical safety assessment
- Toxic effect type:
- dose-dependent
Effects on fertility
Description of key information
In an OECD 422 screening study conducted in rats administered 1,6-divinylperfluorohexane by the oral route (gavage) at up to 1000 mg/kg/day, there were no substance-related findings indicative of adverse effects on the reproductive organs, or reproduction parameters.
Effect on fertility: via oral route
- Endpoint conclusion:
- no adverse effect observed
Effect on fertility: via inhalation route
- Endpoint conclusion:
- no study available
Effect on fertility: via dermal route
- Endpoint conclusion:
- no study available
Effects on developmental toxicity
Description of key information
In an OECD 422 screening study conducted in rats administered 1,6-divinylperfluorohexane by the oral route (gavage) at up to 1000 mg/kg/day, there were no substance-related findings indicative of adverse effects on the pre- or postnatal development.
Effect on developmental toxicity: via oral route
- Endpoint conclusion:
- no adverse effect observed
Effect on developmental toxicity: via inhalation route
- Endpoint conclusion:
- no study available
Effect on developmental toxicity: via dermal route
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Based on the absence of adverse effects on the reproductive parameters and development in the available study, 1,6-Divinylperfluorohexane does require classification for reproductive toxicity according to the criteria of the CLP Regulation EC No. 1272/2008.
Additional information
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