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EC number: 205-406-3 | CAS number: 140-26-1
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Based on the EPI Suite ECOSAR version 1.10, the 96 hours LC50 was estimated to be 2.872 mg/L on fish for substance Phenethyl isovalerate with mortality effects.
But the partition coefficient (log Kow ) value for test substance not ≥ 4 it is found to be in the range 3.71 to 3.9 thus not fulfill the classification criteria of CLP and therefore the target chemical not consider for the aquatic classification.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 2.872 mg/L
Additional information
Based on the Weight of evidence approch for the target substance Phenethyl isovalerate studies are summarized as fallowed :
Based on the EPI Suite ECOSAR version 1.10, the 96 hours LC50 was estimated to be 2.872 mg/L on fish for substance Phenethyl isovalerate with mortality effects.
And in second study which is based on the Danish QSAR database, the short term toxicity in fish for 96 hours LC50 was estimated to be 2.38025 mg/L for substance Phenethyl isovalerate with mortality effects.
But the partition coefficient (log Kow ) value for test substance not≥4 it is found to be in the range 3.71 to 3.9 thus not fulfil the classification criteria of CLP and therefore the target chemical not consider for the aquatic classification.
Above conclusion also support by read across chemical (Cas no.140-11-4) study from peer reviewed journal (U.S.Fish.Wildl.Serv., Sp.Sci.Rep; 124 p., 1963) i.e Short term toxicity study to Cyprinus carpio was carried out for 44 hrs. Test was performed under flow through conditions. After exposure of test animal to different dose conc. i.e, at 68, 130 and 146 mg/l of test chemical benzyl acetate, no effects were observed on mobility of the test animal. Thus, the NOEC value was consider to be 146 mg/l respectively.
Overall all studies concluded that the test substance Phenethyl isovalerate is non toxic to aquatic environment thus not consider for the further classification.
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