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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

The Effective concentration (EC50) for Thiosemicarbazide was found to be 19 mg/L and the NOEC is 2.8mg/L in a 72 hr study conducted on Algae on the basis of effect on growth rate.

Key value for chemical safety assessment

EC50 for freshwater algae:
19 mg/L
EC10 or NOEC for freshwater algae:
2.8 mg/L

Additional information

Toxicity test of thiosemicarbazide was done at two concentration 2.8 mg/L and 19 mg/L for 72 h. The EC50 value for thiosemicarbazide is considered to be 19mg/L and the NOEC is 2.8 mg/L.

Based on the value and biodegradability status, the substance may be classified in aquatic chronic category 3 as per the CLP regulation.