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Solubility in organic solvents / fat solubility

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Description of key information

The test substance was determined to be miscible with standard fat HB 307.

Key value for chemical safety assessment

Additional information

In the key study, the solubility of the test substance in standard fat HB 307 was determined. Because the test substance is miscible with standard fat in a 1:1 ratio (v/v) (as determined during a preliminary test), the main study could not be carried out according to the EEC or OECD guidelines. Hence, an alternative test for the determination of the miscibility of the test substance and standard fat was chosen.

At 3 different ratios test substance / standard fat (v/v), i.e. 0.05; 1 and 20, no phase separation could be observed. All mixtures were clear colourless to slight yellow liquids. The temperature of the measurement was 37.0 +/- 0.5 °C.

Therefore, it was concluded that the test substance was determined to be miscible with standard fat HB 307.