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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Physical & Chemical properties

Partition coefficient

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partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
according to guideline
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
not specified
Principles of method if other than guideline:
The partition coefficient was determined with shake flask method. As analytical method the absorption spectrophotometry was used by which the octanol saturated water phase was analyzed.The study was performed at 25 °C.
GLP compliance:
Type of method:
shake-flask method to: flask method
Partition coefficient type:
Analytical method:
photometric method
log Pow
Partition coefficient:
25 °C
ca. 7
Remarks on result:
other: pH not reported. It is however obvious that a pH around 7 is correct.

pH value not reported.

m-Toluidine has an partition coefficient of 1.40 at 25 °C.
Executive summary:

The partition coefficient was determined by shake-flask method at 25 °C. The analysis was performed with absorption spectrophotometry. The pH-value at which the analysis was performed is not specified.

Description of key information

The logPow of the substance is 1.4.

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
25 °C

Additional information

The experimentally determined logKow is supported by estimated data.

The logarithmic octanol-water partition coefficients (log Kow) for the neutral and protonated form of the substance were predicted using the QSAR calculation of the Estimation Program Interface (EPI) Suite v 4.11. The log Kow was estimated to be 1.62 for the neutral form and -2.06 for the protonated form. These values are in good accordance with the experimental value.

Additionally, handbook data ranked with reliability 2 and 4 are available.