Registration Dossier

Administrative data

Key value for chemical safety assessment

Additional information

Short description of key information:
N,N,N',N'-tetrakis-(2-hydroxyethyl) hexanediamide did not induce a mutagenic effect in S. typhimurium (Hüls Infracor, 1999). Additionally, the test item also induce no structural and numeric chromosomal aberrations in V79 Chinese hamster fibroblasts in vitro, without as well as with an exogenous metabolic activation system (Asta Medica, 1999). The overall conclusion is that N,N,N',N'-tetrakis-(2-hydroxyethyl) hexanediamide is not genotoxic.

It is therefore not considered to be a bacterial mutagen.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

The in vitro genotoxicity studies revealed clearly negative results. Therefore, according to the criteria of EC Regulation 1272/2008 N,N,N',N'-tetrakis-(2-hydroxyethyl) hexanediamide must not be classified.