Registration Dossier
Registration Dossier
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Reaction mass of Tetrasodium 2-[{4-[{4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]-5-sulfonatonaphthalen-1-yl}diazenyl]-7-sulfonatonaphthalen-1-yl}diazenyl]benzene-1,4-disulfonate and Tetrasodium 2-[{4-[{4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]-5-sulfonatonaphthalen-1-yl}diazenyl]-6-sulfonatonaphthalen-1-yl}diazenyl]benzene-1,4-disulfonate
EC number: 916-837-8 | CAS number: -
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
The available information suggests that absorption of FAT 40032/G would primarily take place in the gastrointestinal tract following oral ingestion with some absorption potentially also capable of taking place via damaged skin albeit uptake via intact skin is considered unlikely to occur. Once absorbed, the substance would primarily be distributed in the serum with excretion via the urine and faeces.
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
The absorption, distribution, metabolism and excretion of FAT 20011/E has been predicted and based on the results from the studies conducted provide evidence that absorption of FAT 40032/G would primarily take place in the gastrointestinal tract following oral ingestion. Once absorbed, FAT 40032/G would probably be distributed in the serum. Some absorption may also potentially occur through the skin barrier although low fat solubility would suggest that significant binding to body fat is unlikely. There was no evidence to indicate test item or metabolite influenced hepatic metabolism and excretion of the test substance and/or its metabolites would predominantly be via the urine and faeces.
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