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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Link to relevant study record(s)

Description of key information

Calculation with BCFBAF v3.01 (EPIWIN software by US-EPA):
Bioconcentration Factor (BCF) = 3.16 L/kg (regression-based estimate)
BCF = 0.893 L/kg (Arnot-Gobas method)

Key value for chemical safety assessment

BCF (aquatic species):
3.16 L/kg ww

Additional information

The prediction for the bioconcentration factor (BCF) of the substance 1,2,3-propanetriol, glycidyl ethers was determined by the computer program BCFBAF v3.01 (EPIWIN software) of US-EPA (Chemservice S.A., 2011). Furthermore the whole body primary biotransformation rate estimation for fish was calculated with the notation that the bio half-life normalized to 10 g fish at 15 °C. It is possible to predict the apparent metabolism half-life in fish for three different trophic levels (lower, mid and upper). Using the regression-based estimate (traditional method) a BCF of 3.16 L/kg wet-wt was calculated. Using the Arnot-Gobas method, which is based on the mechanistic first principles, the BCF results in a value of 0.893 L/kg wet-wt. The whole body primary biotransformation rate estimate for fish results in a half-life of 0.00257 days, whereby the bio half-life is normalized to 10 g fish at 15 °C. The rate constant (kM) for 10 g fish is 3.572/day. This is taken into account to predict the apparent metabolism half-life in fish of the test compound. With the Arnot-Gobas method it is possible to differentiate between three trophic levels. For the lower trophic level the BCF results in 0.941 L/kg wet-wt, for a mid trophic level the result is 0.932 L/kg wet-wt and for the higher trophic level 0.893 L/kg wet-wt. It can be concluded that bioaccumulation potential of the test substance in aquatic organisms is negligible.