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EC number: 203-120-3 | CAS number: 103-53-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
In order to determine the classification for hazardous properties related to the aquatic environment, the criteria of the Regulation (EC) No 1272/2008 (CLP) version 2016 in Annex I were accurately followed.
Short-term (acute) aquatic hazard:
For classification, acute toxicity data are available for aquatic invertebrates (Daphnia) and algae:
- Daphnia: EC50 (48h) > 1 mg/L (concentration determination based on water solubility; nominal concentration was 100 mg/L)
- Algae: EC50 (72h, growth rate) > 96.3 µg/L (saturated solution, highest possible concentration tested)
For both species it is concluded that no effects were seen up to water solubility limits of the substance.
The criteria in Table 4.1.0 (a) of Annex I of the CLP Regulation were applied. According to Table 4.1.0 (a) and Note 4, the substance should not be classified for acute aquatic toxicity as the EC50 for both species is above the water solubility.
Long-term (chronic) aquatic hazard:
For chronic classification, there are only chronic data available for one trophic level, algae. As described in Figure 4.1.1 in the CLP regulation (EC No 1272/2008, version 2016), the most stringent outcome of classification according to Table 4.1.0 (b) (i) or (ii) and (iii) should be used.
Table 4.1.0 (b) (i):
The substance is considered to be not readily biodegradable, hence Table 4.1.0 (b) (i) applies, and not Table 4.1.0 (b) (ii).
The chronic EC10 (72h, growth rate) for algae was 62.3 µg/L, which is below the cut-off value for classification as aquatic chronic category 1. Therefore, based on this scheme the substance should be classified for chronic aquatic toxicity, category 1.
Table 4.1.0 (b) (iii):
Classification based on available acute data available for 2 trophic levels and environmental fate data:
- Daphnia: EC50 (48h) > 1 mg/L (concentration determination based on water solubility; nominal concentration was 100 mg/L)
- Algae: EC50 (72h, growth rate) > 96.3 µg/L (saturated solution, highest possible concentration tested.
For both species it is concluded that no effects were seen up to water solubility limits of the substance.
Based on the criteria Table 4.1.0 (b) (iii), the substance should not be classified for chronic aquatic toxicity.
Most stringent classification:
The conclusion is that the substance should be classified for chronic aquatic hazard, category 1 based on the available long-term toxicity information for algae.
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