Registration Dossier
Registration Dossier
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EC number: 204-465-2 | CAS number: 121-33-5
Specific investigations: other studies
Administrative data
- Endpoint:
- specific investigations: other studies
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
Data source
Reference
- Reference Type:
- publication
- Title:
- Biological activity of phenolic compounds. Hepatic cytochrome P-450, cytochrome b5, and NADPH cytochrome c reductase in Chicks and rats fed phenolic monomers, polymers, and glycosides (42134)
- Author:
- Klasing SA, Mora MI, Wilson WC, Fahey GC, Garst JE
- Year:
- 1 985
- Bibliographic source:
- Proceedings of the Society for Experimental Biology and Medicine, 179, 529-538
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- GLP compliance:
- not specified
- Type of method:
- in vivo
Test material
- Reference substance name:
- Reference substance 001
- Details on test material:
- - Test material identity: vanillin from Sigma Corp., St Louis, MO (no other information available)
Constituent 1
Test animals
- Species:
- other: Chicks
- Strain:
- other: New Hampshire x Columbian
- Sex:
- female
Results and discussion
- Details on results:
- Inclusion of 0.5% vanillin in diet of chicks had no effect on animal performance or hepatic measurements compared with controls.
Applicant's summary and conclusion
- Conclusions:
- Vanillin (0.5% in diet) had no effect on chick performance or hepatic measurements.
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