Registration Dossier
Registration Dossier
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EC number: 201-075-4 | CAS number: 78-00-2
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Testing on other microorganisms showed similar EC50 results to other testing.
2 studies provide the weight of evidence argument for the figures quoted:
Marchetti (1978) found an 48hr EC50 of 0.31 mg TEL/L
Wong et al (1979) found an 48hr EC50 of 0.078 mg TEL/L
The values obtained are of a similar level to the testing on Fish, aquatic invertebrates and algae, therefore the values quoted are reasonable
Key value for chemical safety assessment
- EC50 for microorganisms:
- 0.078 mg/L
Additional information
Based on a reduction of oxygen uptake by marine bacterial mixed cultures, a 48-h EC50 value of 0.31 mg TEL/L was determined. In a field trial with zooplankton and algae at a TEL concentration of 0.078 mg/L, all activity was found to be terminated within 48 hours.[r1]
The following information is taken into account for effects on aquatic micro-organisms for the derivation of PNEC:
Testing on other microorganisms showed similar EC50 results to other testing.
Two studies provide the weight of evidence argument for the figures quoted:
Marchetti (1978a) found a 48-h EC50 of 0.31 mg TEL/L.
Wong and Hincks (1979) found a 48-h EC50 of 0.078 mg TEL/L
The values obtained are of a similar level to the testing on fish, aquatic invertebrates and algae.
Value used for CSA:
EC50/LC50 for aquatic micro-organisms: 0.078 mg/L
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