Registration Dossier
Registration Dossier
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EC number: 310-288-2 | CAS number: 161907-78-4 A complex mixture of oxygenated hydrocarbons produced by the distillation of residues from the manufacture of ethylene glycol monoethyl ether. It consists predominantly of a mixture of di-, tri-, tetra- and pentaethylene glycol monoethyl ethers having carbon numbers predominantly in the range C6 to C12 and boiling in the range of approximately 200°C to 300°C (392°F to 572°F).
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Two studies in freshwater for the read across substance 2-(2-(2-ethoxyyethoxy)ethoxy)ethanol: BOD28=92%, BOD20=71%.
3,6,9,12-tetraoxatetradecan-1-ol: QSAR predicts readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
There is no biodegradation information available for the UVCB substance itself. However, ta major component of thesubstance, 2 -(2 -(2 -ethoxyethoxy)ethoxy)ethanol ,was found to be readily biodegradable in a guideline study in freshwater where the BOD28 was 92.1%. The biodegradation was also assessed at a number of concentrations using a non-adapted domestic sewage innoculum in a freshwater medium. Ready degradation was observed with a BOD20 of 71%. In a single study in saltwater using the same substance, evidence of biodegradation was seen with 22% degradation after 20 days. A reliable QSAR predicts that both this substance and the other major component, 3,6,9,12-tetraoxatetradecan-1-ol ,will be readily biodegradable. The available data leads to a reliable conclusion that 3,6,9,12-tetraoxatetradecan-1-ol will be readily biodegradable. Please see the read across justification attached to chapter 13 of the lead registrant dossier for further information on read across within the E series of glycol ethers.
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