Registration Dossier
Registration Dossier
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EC number: 480-410-8 | CAS number: 13482-23-0
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2006-03-23 to 2006-09-11
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- 1992
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 1995
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- >= 4.16 - <= 4.47
- Remarks on result:
- other: miscible with distilled water at 20°C at any ratio.
- Conclusions:
- 4-Methoxycyclohexanone was miscible with distilled water at 20°C at any ratio.
- Executive summary:
The water solubility CS of the test item in distilled water was determined based on the "flask method" described in guideline 92/69/EEC, appendix A.6., OECD-guideline 105. The test item was stirred with distilled water at 20°C and checked visually. The miscibility of 4-Methoxycyclohexanone with distilled water has been tested at the ratios of 1:9; 3:7; 5:5; 7:3 and 9:1. Result of the solubility / miscibility tests: 4-Methoxycyclohexanone was miscible with distilled water at 20°C at any ratio.
Reference
Validity criteria for the measurement of the water solubility:
| Target condition according to guideline OECD 105: | Actual condition according to the study: | Validity criteria met: |
| A substance-specific analytical method is preferred for these determinations, since small amounts of soluble impurities can cause large errors in the measured solubility. Examples of such methods are: gas or liquid chromatography, titration methods, photometric methods, voltametric methods. | The test item was checked visually and no analytical method was used. The test was performed according to OECD TG 105 from 07/1995 - here not analytical measurement was demanded. | Not applicable |
| The pH of each sample should be recorded. | The pH for each sample is reported. | Yes |
| The individual results from each of the three flasks, which should not differ by more than 15%, are averaged. | The test item was miscible at any ratio. | Not applicable. |
Description of key information
4-Methoxycyclohexanone was miscible with distilled water at 20°C at any ratio.
Key value for chemical safety assessment
Additional information
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