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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2005-07-22 - 2005-08-24
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP Guideline study, no deficiencies
Qualifier:
according to
Guideline:
OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
GLP compliance:
yes (incl. certificate)
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic, non-adapted
Details on inoculum:
Inokulum for municipal STP Taunusstein-Bleidenstadt, washed twice with mineral nutirent
Duration of test (contact time):
28 d
Initial conc.:
88 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
CO2 evolution
Details on study design:
Temperature maintained between 20.0-21.7 deg C (mena 20.8 deg C)
Reference substance:
benzoic acid, sodium salt
Parameter:
% degradation (CO2 evolution)
Value:
83
Sampling time:
28 d
Parameter:
% degradation (CO2 evolution)
Value:
61
Sampling time:
12 d
Details on results:
10 d Window was met
Results with reference substance:
Sodium benzoate was degraded 95% after 28d, the 10d window was met after 5d
Validity criteria fulfilled:
yes
Interpretation of results:
readily biodegradable
Conclusions:
The registration substance was tested in an OECD 301B CO2 Evolution test and was found to be readily biodegradable within the 10d window.

Description of key information

BIODEGRADATION IN WATER: SCREENING TEST

The registration substance is readily biodegradable in an OECD 301B CO2 Evolution test fulfilling the 10d window. CO2 evolution was 83% after 28d and has reached the pass level of 60% CO2 formation after 12d already.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information