Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 205-553-3 | CAS number: 142-71-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Additional information
- According to Directive 67/548/EEC: Corrosive (C). R34, Causes burns.
- According to CLP/GHS: Category 1B Corrosive, H314, Causes severe skin burns and eye damage.
- According to Directive 67/548/EEC: Irritant (Xi). R41, risk of serious damage to eyes.
- According to CLP/GHS: Eye Damage 1, H318: Causes serious eye damage.
Skin irritation/corrosivity:
A GLP-compliant in-vitro skin corrosivity test was conducted in accordance with the requirements of OECD Guideline 431 and EU Method B.40 BIS (Warren, 2012b). Data were presented in the form of percentage viability (MTT reduction in the test item treated tissues relative to negative control tissues). The relative mean viability of the test item treated tissues was as follows: 240 minutes exposure, 12.1%; 60 minutes exposure, 21.4%; 3 minutes exposure, 54.4%. On this basis it is concluded that copper di(acetate) is corrosive in contact with skin and that the following classification applies:
Eye irritation/corrosivity:
A GLP-compliant eye irritation test was carried out in a single rabbit in accordance with internationally accepted guidelines (Bradshaw, 2012c). The persistence of reactions in the treated eye at the 21 -Day observation was considered to be indicative of irreversible ocular damage. The test item was considered to be corrosive to the rabbit eye and was classified as follows:
Justification for classification or non-classification
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