Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-553-3 | CAS number: 142-71-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Additional information
- According to Directive 67/548/EEC: Corrosive (C). R34, Causes burns.
- According to CLP/GHS: Category 1B Corrosive, H314, Causes severe skin burns and eye damage.
- According to Directive 67/548/EEC: Irritant (Xi). R41, risk of serious damage to eyes.
- According to CLP/GHS: Eye Damage 1, H318: Causes serious eye damage.
Skin irritation/corrosivity:
A GLP-compliant in-vitro skin corrosivity test was conducted in accordance with the requirements of OECD Guideline 431 and EU Method B.40 BIS (Warren, 2012b). Data were presented in the form of percentage viability (MTT reduction in the test item treated tissues relative to negative control tissues). The relative mean viability of the test item treated tissues was as follows: 240 minutes exposure, 12.1%; 60 minutes exposure, 21.4%; 3 minutes exposure, 54.4%. On this basis it is concluded that copper di(acetate) is corrosive in contact with skin and that the following classification applies:
Eye irritation/corrosivity:
A GLP-compliant eye irritation test was carried out in a single rabbit in accordance with internationally accepted guidelines (Bradshaw, 2012c). The persistence of reactions in the treated eye at the 21 -Day observation was considered to be indicative of irreversible ocular damage. The test item was considered to be corrosive to the rabbit eye and was classified as follows:
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
