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Water solubility

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water solubility
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is hydrolytically unstable at pH 4, 7 and 9 (half-life less than 12 hours)
water solubility
Type of information:
experimental study
Adequacy of study:
supporting study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
equivalent or similar to guideline
EU Method A.6 (Water Solubility)
Version / remarks:
84/449/EWG, A.6 (Kolben Method)
Key result
Water solubility:
58 mg/L
20 °C
Water solubility of 58 mg/l reported at 20°C

Description of key information

Testing is not possible as in contact with water the substance hydrolyses instantly (Ref: “Hydrolysis of Test Item", GLP report no. 09.093 from Ciba Inc.,(TAOH),2009.

For CSA use purposes only, water solubility of 58 mg/l 20°C as reported in the supporting study has been used.

Key value for chemical safety assessment

Water solubility:
58 mg/L
at the temperature of:
20 °C

Additional information

The water solubility of the degradation products are known and given as follows:

0.014 g/L at 20°C at pH 4.8  (Bis-(2-ethylhexyl)amine) -Ref: OXEA GmbH, Report No: AN-ASB 0496, 12 April 2010

547 g/L at 22°C  (1H-1,2,4 -triazole) - Ref:GESTIS Substance Database. (IFA)

400 g/L at 20°C  (Formaldehyde) - Ref:SRC PhysProp Database. (Experimental data, Ref.: Pickrell, JA ET AL. 1983).