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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Water solubility

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water solubility
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is hydrolytically unstable at pH 4, 7 and 9 (half-life less than 12 hours)
water solubility
Type of information:
experimental study
Adequacy of study:
supporting study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
equivalent or similar to guideline
EU Method A.6 (Water Solubility)
Version / remarks:
84/449/EWG, A.6 (Kolben Method)
Key result
Water solubility:
58 mg/L
20 °C
Water solubility of 58 mg/l reported at 20°C

Description of key information

Testing is not possible as in contact with water the substance hydrolyses instantly (Ref: “Hydrolysis of Test Item", GLP report no. 09.093 from Ciba Inc.,(TAOH),2009.

For CSA use purposes only, water solubility of 58 mg/l 20°C as reported in the supporting study has been used.

Key value for chemical safety assessment

Water solubility:
58 mg/L
at the temperature of:
20 °C

Additional information

The water solubility of the degradation products are known and given as follows:

0.014 g/L at 20°C at pH 4.8  (Bis-(2-ethylhexyl)amine) -Ref: OXEA GmbH, Report No: AN-ASB 0496, 12 April 2010

547 g/L at 22°C  (1H-1,2,4 -triazole) - Ref:GESTIS Substance Database. (IFA)

400 g/L at 20°C  (Formaldehyde) - Ref:SRC PhysProp Database. (Experimental data, Ref.: Pickrell, JA ET AL. 1983).