1-(N,N-bis(2-ethylhexyl)aminomethyl)-1,2,4-triazole

Water solubility

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

water solubility

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is hydrolytically unstable at pH 4, 7 and 9 (half-life less than 12 hours)

Reference 2

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

comparable to guideline study with acceptable restrictions

Qualifier:

equivalent or similar to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

84/449/EWG, A.6 (Kolben Method)

Key result

Water solubility:

58 mg/L

Temp.:

20 °C

Conclusions:

Water solubility of 58 mg/l reported at 20°C

Description of key information

Testing is not possible as in contact with water the substance hydrolyses instantly (Ref: “Hydrolysis of Test Item", GLP report no. 09.093 from Ciba Inc.,(TAOH),2009.

For CSA use purposes only, water solubility of 58 mg/l 20°C as reported in the supporting study has been used.

Key value for chemical safety assessment

Water solubility:

58 mg/L

at the temperature of:

20 °C

Additional information

The water solubility of the degradation products are known and given as follows:

0.014 g/L at 20°C at pH 4.8  (Bis-(2-ethylhexyl)amine) -Ref: OXEA GmbH, Report No: AN-ASB 0496, 12 April 2010

547 g/L at 22°C  (1H-1,2,4 -triazole) - Ref:GESTIS Substance Database. (IFA)

400 g/L at 20°C  (Formaldehyde) - Ref:SRC PhysProp Database. (Experimental data, Ref.: Pickrell, JA ET AL. 1983).