Registration Dossier

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Parent substance EC 401 -280 -0

Stability

The results of the Hydrolysis study (Ciba, 2009) show that the test item hydrolyses rapidly in water. The study includes two sets of experiments (Ivestigation by LC/MS and investigation by H-NMR). Both experiments showed that hydrolysis of the test item is very fast. The proposed degradation products are bis(2 -ethylhexyl)amine, 1H-1,2,4 -triazole and formaldehyde (as methanediol).

Biodegradation

The ready biodegradability of the test item was assessed according to OECD guideline 301 B. The test revealed that no biodegradation occurred. Additionally the chemical oxygen demand was investigated according to DIN 38 409. A COD of 2.55 g COD/ g test substance was calculated.

Bioaccumulation

Due to the results from different QSAR calculations significant bioaccumulation is not expected.

Transport and distribution

No reliable data on substance EC 401 -280 -0 are available. However, as this substance hydrolyses very fast only the degradation products are considered.

Environmental fate data on the degradation products were additionally evaluated. After hydrolysis the degradation products will consist mainly of bis(2-ethylhexyl)amine (ca 70%), about 20% of the hydrolysate will be 1H-1,2,4-triazole and about 10% formaldehyde (taking into account the individual molecular masses).

Hydrolysis products:

bis(2 -ethylhexyl)amine

Stability

Due to the structural properties of the substance, hydrolysis is not expected under environmental conditions.

Biodegradation

The test substance is regarded to be not readily biodegradable, but moderately biodegradable.

Bioacccumulation

Significant accumulation in organisms is not expected.

Transport and distribution

Adsorption to the solid soil phase is expected.

From the water surface, the substance will slowly evaporate into the atmosphere at pH 9.0 but not at pH 7.0 and lower.

According to the results of the Mackay LEVEL 1 calculation, over time the substance will preferentially distribute into the compartments sediment (50%) and soil (50%). However, since the model does not consider the ionic form of the molecule at environmental relevant pH conditions (5 -9), the model may underestimate distribution into water.

1H-1,2,4 -triazole

Stability

The hydrolysis half-life of 1H-1,2,4 -triazole is > 30days (ECHA disseminated REACH dossier, 2014).

Biodegradation

The substance is not readily biodegradable but significant degradation was observed in a field study in different soils (ECHA disseminated REACH dossier, 2014).

Bioaccumulation

Due to the results of QSAR calculations, significant accumulation in organisms is not expected. The logPow of 0.35 (Hansch et al 1995) indicates a low bioaccumulation potential.

Transport and distribution

Mobility in soil is expected. No data on Henry's Law constant and distribution modelling are available.

Formaldehyde

Stability

Hydrolysis is due to the chemical structure not expected.

Biodegradation

Formaldehyde is expected to be readily biodegradable at low concentrations (Gerike 1990).

Bioaccumulation

In tests on different fish species and a shrimp no bioaccumulation was observed. The logPow of 0.35 (Hansch et al 1995) indicates a low bioaccumulation potential.

Transport and distribution

Moderate to high mobility in soil is expected. From the water phase the substance will not evaporate into the atmosphere. Using simple environmental models based on fugacity, the main target for environmental distribution will be water.