Registration Dossier
Registration Dossier
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EC number: 205-569-0 | CAS number: 142-88-1
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The effective concentration (EC50) for piperazine adipate for Pseudokirchneriella subcapitata at 72 hours is estimated to be 119.68 mg/L for effect on growth. Based on this value it can be concluded that piperazine adipate is not toxic to aquatic environment based the criteria given by CLP regulation.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 119.68 mg/L
- EC10 or NOEC for freshwater algae:
- 37.85 mg/L
Additional information
Summary of weight of evidence - Toxicity to aquatic algae and cyanobacteria
No of studies reviewed for Toxicity to aquatic algae and cyanobacteria from reliable sources having Klimish rating 2 and 4
The summary if the results are presented below
Sr. No |
Endpoint name |
Value |
Units |
Species |
Source |
1 |
EC50 |
119.68 |
mg/l |
Pseudokirchneriella subcapitata |
Prediction report |
2 |
NOEC |
37.85 |
mg/l |
Pseudokirchneriella subcapitata |
Prediction report |
3 |
EC50 |
356.64 |
mg/l |
green algae |
ECOSAR |
4 |
EC50 |
479.62 |
mg/l |
Pseudokirchneriella subcapitata |
DEPA |
Based on the above values it can be seen that the lethal concentration (LC50) values varies between 119.68 to 479.62 mg/l. From above values it can be concluded that the piperazine adipate is not toxic to aquatic environment based on the classification criteria of CLP regulation.
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