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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

The growth inhibition concentration (IGC50) for piperazine adipate for Tetrahymena pyriformis at 48 hours is estimated to be 916.19 mg/L for effect on growth. Based on this value it can be concluded that piperazine adipate is not toxic to aquatic environment based the criteria given by CLP regulation

Key value for chemical safety assessment

EC50 for microorganisms:
916.19 mg/L

Additional information

Summary of weight of evidence - Toxicity to microorganisms

No of studies reviewed for Toxicity to microorganisms from reliable sources having Klimish rating 2 and 4

The summary if the results are presented below

 

Sr. No

Endpoint name

Value

Units

Species

Source

1

EC50

916.19

mg/l

Tetrahymena pyriformis

Prediction report

2

EC50

1467.23

mg/l

Tetrahymena pyriformis

DEPA

 

Based on the above values it can be seen that the lethal concentration (LC50) values varies between 916.62 to 1467.23 mg/l. From above values it can be concluded that the piperazine adipate is not toxic to aquatic environment based on the classification criteria of CLP regulation.