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Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: application method is not relevant for the human situation

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1986

Materials and methods

Principles of method if other than guideline:
other: no further data
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
m-cresol
EC Number:
203-577-9
EC Name:
m-cresol
Cas Number:
108-39-4
Molecular formula:
C7H8O
IUPAC Name:
3-Methylphenol
Details on test material:
no data on purity

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
other: migrated dataset
Doses:
200-3200 mg/kg bw as 10 % solution in 2 % NaCS
No. of animals per sex per dose:
10
Control animals:
other: migrated dataset

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
400 mg/kg bw

Any other information on results incl. tables

RS-Freetext:
Signs of intoxication:
labored respiration, cyanosis, dark eyes, prostration
time of death: 8 hrs to 1 day

Applicant's summary and conclusion

Executive summary:

migrated dataset