Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-559-3 | CAS number: 122-63-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Short term toxicity to fish
Fish Acute Toxicity test according to OECD Guideline 203 was conducted for Benzyl Propionate. The nominal concentration selected for the experiment were and test fish were exposed to 6.25 mg/L, 12.5 mg/L, 25 mg/L, 50 mg/L & 100 mg/L concentrations for 96 hours. The median lethal concentration (LC50) for Benzyl Propionate on Danio rerio in a 96 hours study on the basis of mortality effect was found to be >12.5 mg/L. Thus, on the basis
of this LC50 value and according to CLP criteria for aquatic classification of the substance, it is concluded
that the substance, is classified under aquatic chronic 3 category
Benzyl Propionate (CAS No. 122 -63 -4) exhibits short term toxicityto fish.LC0 (96 hours) (highest loading at which no mortality was observed) = 12.5 mg/L
LC50 (96 hours) Experimental = >12.5 mg/L
Long term toxicity to fish
The lethal concentration for 50 percent mortality (LC 50, 14 days) value of benzyl propionate in fish was reported as 642.3 mg/L. Based on this value and considering that benzyl propionate is readily bio-degradable in water it can be predicted that this chemical will not exhibit long term toxicity to fish.
Short term toxicity to aquatic invertebates
The lethal concentration for 50 percent mortality (LC 50, 48 hr) value of benzyl propionate in the aquatic invertebrate Daphnia magna was reported as 20 mg/L but the BCF value of benzyl propionate reported were not >= 500 and neither was the Log Kow value greater than or equal to 4.. Thus considering the conditions mentioned in the CLP regulation for classification; benzyl propionate could be assumed to be non toxic to the aquatic invertebrate Daphnia magna.
Long term toxicity to aquatic invertebates
The chronic value for long term toxicity(21 days) to aquatic invertebrate daphnia magna was reported as 11.5 mg/L.
Toxicity to aquatic algae and cyanobacteria
The effect of test substance Benzyl propionate, CAS No. 122 -63 -4 was studied on the growth of fresh water green algaChlorella vulgaris.The study was conducted following OECD guideline 201- Alga growth inhibition test. The test concentration chosen for the study were 4.32mg/l, 10.88 mg/l, 27.2mg/l, 68mg/l, 170mg/l and 425mg/l were prepared using stock solution of the test substance using de-ionized water. The green alga was exposed to the test concentration for a period of 72 hours to observe average specific growth rate and % growth inhibition under the effect of test substance. EC50 calculated from equation through probit analysis was observed to be 138.96 mg/L.
Toxicity to micro-organisms
The inhibitory growth concentration (IGC50) value of benzyl propionate in Tetrahymena pyriformis in a 46 hr study on growth inhibition effect was estimated to be 134.091 mg/L.
Additional information
Short term toxicity to fish
Fish Acute Toxicity test according to OECD Guideline 203 was conducted for Benzyl Propionate. The nominal concentration selected for the experiment were and test fish were exposed to 6.25 mg/L, 12.5 mg/L, 25 mg/L, 50 mg/L & 100 mg/L concentrations for 96 hours. The median lethal concentration (LC50) for Benzyl Propionate on Danio rerio in a 96 hours study on the basis of mortality effect was found to be >12.5 mg/L. Thus, on the basis
of this LC50 value and according to CLP criteria for aquatic classification of the substance, it is concluded
that the substance, is classified under aquatic chronic 3 category
Benzyl Propionate (CAS No. 122 -63 -4) exhibits short term toxicityto fish.LC0 (96 hours) (highest loading at which no mortality was observed) = 12.5 mg/L
LC50 (96 hours) Experimental = >12.5 mg/L
Long term toxicity to fish
The lethal concentration for 50 percent mortality (LC 50, 14 days) value of benzyl propionate in fish was reported as 642.3 mg/L. Based on this value and considering that benzyl propionate is readily bio-degradable in water it can be predicted that this chemical will not exhibit long term toxicity to fish.
Short term toxicity to aquatic invertebates
The lethal concentration for 50 percent mortality (LC 50, 48 hr) value of benzyl propionate in the aquatic invertebrate Daphnia magna was reported as 20 mg/L but the BCF value of benzyl propionate reported were not >= 500 and neither was the Log Kow value greater than or equal to 4.. Thus considering the conditions mentioned in the CLP regulation for classification; benzyl propionate could be assumed to be non toxic to the aquatic invertebrate Daphnia magna.
Long term toxicity to aquatic invertebates
The chronic value for long term toxicity(21 days) to aquatic invertebrate daphnia magna was reported as 11.5 mg/L.
Toxicity to aquatic algae and cyanobacteria
The effect of test substance Benzyl propionate, CAS No. 122 -63 -4 was studied on the growth of fresh water green algaChlorella vulgaris.The study was conducted following OECD guideline 201- Alga growth inhibition test. The test concentration chosen for the study were 4.32mg/l, 10.88 mg/l, 27.2mg/l, 68mg/l, 170mg/l and 425mg/l were prepared using stock solution of the test substance using de-ionized water. The green alga was exposed to the test concentration for a period of 72 hours to observe average specific growth rate and % growth inhibition under the effect of test substance. EC50 calculated from equation through probit analysis was observed to be 138.96 mg/L.
Toxicity to micro-organisms
The inhibitory growth concentration (IGC50) value of benzyl propionate in Tetrahymena pyriformis in a 46 hr study on growth inhibition effect was estimated to be 134.091 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

EU Privacy Disclaimer
This website uses cookies to ensure you get the best experience on our websites.