Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
dermal absorption
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
Danish QSAR study for CAS No.: 122-63-4
Author:
Danish EPA Model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:- EPI Suite (DERMWIN) Various versions of EPI Suite dating back from 1990-2004

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Modelling database
Principles of method if other than guideline:
The amount of dermal absorption in mg per square cm of skin per application
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzyl propionate
EC Number:
204-559-3
EC Name:
Benzyl propionate
Cas Number:
122-63-4
Molecular formula:
C10H12O2
IUPAC Name:
benzyl propionate
Details on test material:
- Name of test material: benzyl propionate
- Molecular formula: C10H12O2
- Molecular weight: 164.20 g/mole
- Substance type: Organic
- Physical state: Liquid
Radiolabelling:
not specified

Test animals

Species:
other: no data
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Duration of exposure:
no data
Doses:
no data
No. of animals per group:
no data

Results and discussion

Any other information on results incl. tables

Dermal absorption: 0.00700 mg/cm2/event (MODERATE)

Applicant's summary and conclusion

Conclusions:
The dermal absorption of benzyl propionate is estimated to be 0.00700 mg/cm2/event indicating that the substance is moderately absorbed.
Executive summary:

The dermal absorption of benzyl propionate is estimated to be 0.00700 mg/cm2/event indicating that the substance is moderately absorbed.

Categories Display