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Toxicity to microorganisms

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Description of key information

The inhibition of the degradation activity of activated sludge is not anticipated when 1.2 -epoxybutane introduced in appropriate low concentrations.

Key value for chemical safety assessment

Additional information

The toxicity of 1.2 -epoxybutane on microorganisms was tested in an respiration inhibition test with activated domestic sludge, according to OECD guideline 209 [BASF AG, 1999]. The EC20 for respiration inhibition was determined to be approximately 160 mg/L 1.2 -epoxybutane.

Additional informations on the toxicity to microorganisms are available from growth inhibition tests with Pseudomonas putida [BASF AG, 1988]. The 17 h EC10 values for the cell growth inhibition of Pseudomonas putida was 2920 mg/L.