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Registration Dossier
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EC number: 225-863-2 | CAS number: 5124-30-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Monitoring data
Administrative data
- Endpoint:
- monitoring data
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Basic data given
Data source
Reference
- Title:
- No information
- Author:
- Henriks-Eckerman M-L, Vaelimaa J, Rosenberg C, Peltonen K, Engstroem K (2002). Expsure to airborne isocyanates and other thermal degradation products at polyurethane-processing workplaces. J. Environ. Monit. 4, 717-721.
Materials and methods
- Principles of method if other than guideline:
- LC/UV
- Type of measurement:
- concentration at contaminated site
- Media:
- air
Test material
- Reference substance name:
- 4,4'-methylenedicyclohexyl diisocyanate
- EC Number:
- 225-863-2
- EC Name:
- 4,4'-methylenedicyclohexyl diisocyanate
- Cas Number:
- 5124-30-1
- Molecular formula:
- C15H22N2O2
- IUPAC Name:
- 1,1'-methylenebis(4-isocyanatocyclohexane)
Constituent 1
Results and discussion
Any other information on results incl. tables
RS-Freetext:
Traces of 4,4'-methylenedicyclohexyl diisocyanate (up to 2 µg/m3) were detected as a thermolytic degradation product during joint welding of polyurethane floor covering in a small room without ventilation in a car repair shop
Applicant's summary and conclusion
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