Registration Dossier
Registration Dossier
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EC number: 201-122-9 | CAS number: 78-51-3
Endpoint summary
Administrative data
Description of key information
Additional information
Standardised acute toxicity tests were performed with tris(2-butoxyethyl) phosphate (TBEP), on earthworm (OECD 207) and three different plant species (OECD 208) giving an 14d-LC50 of 544 mg/kg dry soil and a 21d-ER50 = 46.8 mg/kg dry soil (corresponding to 165.75 mg/kg after organic carbon normalisation), respectively.
The registered substance is readily biodegradable and doesn't have a high potential to adsorb to soil therefore consideration of degradation products and long term testing according to Annex X does not appear scientifically justified.
However, as some effects were measured on invertebrates and plants further testing is proposed on soil micro-organisms (OECD 216) in order to cover different habitats and feeding modes in the soil as well as taxonomic groups. At the time being, there are no indications that TBEP will pose a specific hazard to terrestrial arthropods.
Based on low experimental BCF in fish, bioaccumulation of TBEP is not expected. In addition, the acute mammalian toxicity is low and there are no indications that the registered substance will pose a specific hazard to birds.
Therefore, in accordance with annex XI in REACH regulation, further testing on terrestrial arthropods and birds does not appear scientifically necessary.
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