Tetramethylammonium hydroxide

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

18 September 2012 - 17 December 2012

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.10 (Flammability (Solids))

Version / remarks:

(2008)

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: UN ST/SG/AC.10/11/Rev.5: Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Part III Paragraph 33.2.1.4 “ Test N.1: “Test method for readily combustible solids” (2009)

Deviations:

no

GLP compliance:

yes

Key result

Test procedure:

burning rate test: preliminary screening test

Remarks on result:

other: The substance does ignite but does not propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the test period.

The flame of the gas burner did ignite the test substance pile. The test substance melted, burned with a blue flame and turned into an orange/brown residue. After removal of the ignition source, the flame extinguished immediately and no propagation of combustion was observed.

Interpretation of results:

other: not classified based on CLP or GHS criteria

Conclusions:

The substance was determined to be not highly flammable.

Executive summary:

The flammability of the solid substance was determined a GLP study according to EC A.10 and UN Test N.1. In the preliminary screening test, the substance did not propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the test period. The substance was determined to be not highly flammable.

Reference 2

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the experience in production or handling shows that the substance does not react with water, e.g. the substance is manufactured with water or washed with water

Justification for type of information:

JUSTIFICATION FOR DATA WAIVING

An expert statement has been issued in which it was concluded that the substance is ‘not highly flammable’ in contact with water.
-Expert statement: included in study report (see Data Source)
-Expert: M.J.C. Brekelmans, MSc. (WIL Research Europe B.V., The Netherlands)


Expert statement
 
A test substance is considered highly flammable when it ignites spontaneously in contact with water, or evolves a flammable gas at a minimum rate of ≥ 1 litre/kg of the substance per hour.

The test substance does not contain groups that might lead to ignition in contact with water and/or to the evolution of a flammable gas. Moreover the test substance was dissolved in water during the determination of the water solubility (see endpoint 4.8). It demonstrated that the test substance does not ignite spontaneously in contact with water.
 
In conclusion, TMAH pentahydrate is considered ‘not highly flammable’ in contact with water.

Reason / purpose for cross-reference:

data waiving: supporting information

Reason / purpose for cross-reference:

data waiving: supporting information

GLP compliance:

yes

Reference 3

Endpoint:

pyrophoric solids

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is known to be stable in contact with air at room temperature for prolonged periods of time (days) and hence, the classification procedure does not need to be applied

Justification for type of information:

JUSTIFICATION FOR DATA WAIVING

An expert statement has been issued in which it was concluded that the substance has no pyrophoric properties.
-Expert statement: included in study report (see Data Source)
-Expert: M.J.C. Brekelmans, MSc. (WIL Research Europe B.V., The Netherlands)


Expert Statement
 
A test substance is considered pyrophoric when it ignites within five minutes of coming in contact with air.
 
The test substance does not contain groups that might lead to ignition in contact with air. Moreover the test substance was handled under normal laboratory conditions during the determination of the physico-chemical properties. It demonstrated that the test substance does not ignite in contact with air.
 
In conclusion, TMAH pentahydrate has no pyrophoric properties.

GLP compliance:

yes

Description of key information

Not highly flammable (EC A.10 and UN Test N.1: preliminary screening test)

No pyrophoric properties (based on experience in handling and on structural features).

Not highly flammable in contact with water (based on experience in handling and on structural features).

Key value for chemical safety assessment

Flammability:

non flammable

Justification for classification or non-classification

Because not readily combustible in the UN N.1 test, no classification is required for the CLP hazard 'Flammable solid'.

-No classification is required for the CLP hazard 'Pyrophoric solids' or 'Substances which in contact with water emits flammable gases'. The substance does not contain any chemical groups indicating flammability in contact with water or indicating pyrophoric properties. Experience during handling confirmed this.

-Because of the melting temperature 160°C, the substance need not be considered for CLP classification in the 'Self-heating substances' class. .

In conclusion, the substance does not have to be classified for flammability under the CLP Regulation (EC) No. 1272/2008 including its amendments.