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Physical & Chemical properties

Water solubility

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Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Principles of method if other than guideline:
No specification of method
GLP compliance:
no
Type of method:
other: experimental result
Water solubility:
71 g/L
Temp.:
25 °C
pH:
ca. 4 - 6
Water solubility:
71 g/L
Temp.:
25 °C
pH:
2
Water solubility:
69.6 g/L
Temp.:
25 °C
pH:
1
Water solubility:
54.4 g/L
Temp.:
25 °C
pH:
0
Details on results:
Solubility based upon averages of at least 2 trials. pH's of 2, 1, and 0 were calculated from 0.01 M HCl, 0.1 HCL and 1.0 M HCl solutions, respectively.

 

Table 1: Solubility of hydroquinone in water and HCl in g/L

 

Solvent

1

2

3

4

5

Average.

Mol/L

Water

70.94

70.91

71.12

70.86

 

71.0

0.645

0.01MHCl

70.60

71.28

71.36

70.28

71.46

71.0

0.645

0.1MHCl

69.78

69.44

 

 

 

69.6

0.633

1.0MHCl

54.36

54.42

 

 

 

69.6

0.494

 

According to the data from this scientific publication, the water solubility for hydroquinone at 25 °C is 71 g/L at a pH of between 4 -6. Based on pKa values the pH of hydroquinone in solution is between 4 and 6.Water solubility was determined for 71 g/L at a pH of 2; 69.6 g/L at a pH of 1; and 54.4 g/L at a pH of 0.

Conclusions:
Interpretation of results (migrated information): very soluble (> 10000 mg/L)
According to the data from scientific publication, the water solubility for hydroquinone at 25°C is 71 g/L at a pH of between 4-6, 71 g/L at a pH of 2, 69.6 g/L at a pH of 1, and 54.4 g/L at a pH of 0. According to the classification scheme, hydroquinone is very soluble in water.
Executive summary:

According to the data from scientific publication, the water solubility for hydroquinone at 25°C is 71 g/L at a pH of ca. 4-6. According to the classification scheme, hydroquinone is very soluble in water.

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
peer-reviewed
Principles of method if other than guideline:
No specification of method.
GLP compliance:
not specified
Type of method:
other: data from peer-reviewed database
Water solubility:
72 g/L
Temp.:
25 °C
Remarks on result:
other: No data on pH were provided
Details on results:
No information on pH given.

According to the data from this peer-reviewed database, the water solubility of hydroquinone is 72 g/L at 25°C.

Further values are cited, which are not consistent and were obviosly not considered as valid by the HSDB authors: 3.85 g/L at 0 °C; 5.12 g/L at 10 °C; 5.40 g/L at 15 °C; 6.72 g/L at 20°C; 8.76 g/L at 30 °C; 11.5 g/L at 40 °C; 25.9 g/L at 60 °C; 46.8 g/L at 80 °C; 66.4 g/L at 100 °C. According to another source, water solubility at 25°C is 7%.

Conclusions:
Interpretation of results (migrated information): very soluble (> 10000 mg/L)
According to the data from this peer-reviewed database, the water solubility of hydroquinone is 72 g/L at 25 °C.
Executive summary:

According to the data from this peer-reviewed database, the water solubility of hydroquinone is 72 g/L at 25 °C.

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
peer-reviewed
Principles of method if other than guideline:
No specification of method.
GLP compliance:
not specified
Type of method:
other: data from peer-reviewed database
Water solubility:
72 g/L
Temp.:
25 °C
Remarks on result:
other: No data on pH were provided
Details on results:
No information on pH given.

According to this peer-reviewed database, the water solubility of hydroquinone is 72 g/L at 25 °C.

Conclusions:
Interpretation of results (migrated information): very soluble (> 10000 mg/L)
According to this peer-reviewed database, the water solubility of hydroquinone is 72 g/L at 25 °C. According to the classification scheme, hydroquinone is very soluble in water.
Executive summary:

According to this peer-reviewed database, the water solubility of hydroquinone is 72 g/L at 25 °C. According to the classification scheme, hydroquinone is very soluble in water.

Description of key information

72 g/L at 25°C

Key value for chemical safety assessment

Water solubility:
72 000 mg/L
at the temperature of:
25 °C

Additional information

Reliable data from a publication documented in sufficient detail and peer-reviewed sources